Metafolin®

A highly bioavailable form of folate for expectant mothers and infants.

Methylfolate for Maternal Nutrition

At dsm-firmenich, we know that healthy babies start with healthy pregnancies. Low folate status during pregnancy is a risk factor in the development of neural tube defects (NTD) in the fetus. Additionally, high levels of folic acid during gestation are associated with insulin resistance and obesity at 5 years of age. Methylfolate increases blood folate levels to a greater extent than folic acid. Metafolin®, a registered trademark of Merck KGaA, Darmstadt, Germany1, is a highly bioavailable form of folate for expectant mothers, offered as part of our Early Life Nutrition solutions.

Giving moms and babies a healthy start with

Download our latest infographic to discover how Metafolin® can support healthy pregnancies more effectively than folic acid.
Giving moms and babies a healthy start with Calcium L-Methylfolate (Metafolin®)

Download our latest infographic to discover how Metafolin® can support healthy pregnancies more effectively than folic acid.

Potential claims

for maternal nutrition

Metafolin® has better absorption than folic acid

Metafolin® is like the form of folate found in most foods

Metafolin® helps maintain healthy red blood cells

Metafolin® is more bioavailable than folic acid in studies of women of childbearing years

Metafolin® is not expected to mask a potential vitamin B12 deficiency

Metafolin® supports healthy cell division

Methylfolate for Infant Nutrition

Moms are looking for reassurance and trust from the nutritional solutions they choose for their babies. Did you know that a top driver for infant formula purchase preference is how close the product is to breast milk?* Methylfolate is the predominant folate source in breast milk. Metafolin® INF is a highly bioavailable form of folate for infants, supporting infant brain development.

*New DSM Infant/Toddler U&A Study (2021) & Maternal Study (2022)

Supporting infant growth with Calcium L-Methylfolate (Metafolin®)

Download our latest infographic to learn more about the predominant source of folate in breastmilk.

Potential claims

Metafolin® is nature-identical to the predominate form of folate found in breastmilk

Metafolin® is nature-identical to the predominate form of folate in umbilical cord blood

Metafolin®-containing formulas support infant growth, as well as folic acid-containing formula

1. Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany. 

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