From taste to adherence

Sustained patient adherence is essential to ensure therapeutic efficacy but the impact of bitterness on treatment compliance is frequently underestimated. More than 60% of APIs are classified as bitter* and conventional taste-masking strategies are limited by factors such as sensory saturation.

This webinar explores precisely these challenges. We will focus on patient-centric formulation and innovations in flavors and taste modulation for pharmaceutical drug development, with expert insights from leading researchers and a closer look at our ModulaSENSE® Bitter receptor-based screening solution.

This session will cover:
 

1. Key challenges in oral drug product development
   Examine the technical and regulatory factors that shape oral formulation development, from EMA and FDA requirements, through to formulation constraints that affect patient adherence across pediatric, geriatric, and chronic-therapy populations.
2. Palatability as a determinant of adherence
   Poor palatability is a recognized cause of non-adherence and can compromise patient retention in clinical trials, affecting data quality and study outcomes. We will examine approaches to taste assessment and modulation, the value of addressing palatability early in development, and the technical implications of partner selection during formulation design.
3. A closer look at ModulaSENSE® Bitter
   Explore ModulaSENSE® Bitter, our receptor-based screening solution that detects and quantifies bitterness at the molecular level before sensory testing - helping elevate drug palatability and improving patient adherence.

Speakers
 

1. Catherine Tuleu: Docteur en Pharmacie, PhD - Professor in Pediatric Pharmaceutics Postgraduate Research Tutor at UCL School of Pharmacy.
2. Remco Havermans: PhD, professor at Maastricht University Campus Venlo, specializing in taste and eating behavior.
3. Francisco Andre: Senior Manager, Application, HNC Taste EMEA, dsm-firmenich.
4. Pierre-Louis Bardonnet: Technical Business Development Pharma, dsm-firmenich