Health expectancy series

Part 2: Redefine aging with nutrition

Health expectancy series - Part 2: Redefine aging with nutrition

Most of us face the reality of chronic illness and declining health in our later years. But what if aging didn’t have to mean a loss of vitality? Groundbreaking science reveals how targeted nutrients can extend our health expectancy—the years we enjoy robust, vibrant health—empowering us to make our senior years truly the best of our lives.

In this insightful second installment of our three-part series, we dive deep into the latest aging theories and reveal how supplement innovators can harness this knowledge to develop breakthrough solutions. Explore how addressing the root processes of aging and disease opens new frontiers for brands eager to lead in the emerging health expectancy market.

Download the whitepaper now to unlock the potential of nutrient-driven innovation and inspire a healthier, more fulfilling future.

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1. UN. Decade of Healthy Ageing (2021–2030).

2. Ahlawat Hemant, Darcovich Anthony, Dewhurst Martin, Feehan Ellen, Hediger Victor, and Maud Madeline. “Age is just a number:  How Older Adults View Healthy Aging.” McKinsey Health Institute (2023).

3. Bruins Maaike, Van Dael Peter, and Eggersdorfer Manfred.  “The Role of Nutrients in Reducing the Risk for Noncommunicable Diseases during Aging.” Nutrients 11,  no. 1 (2019): 84.

4. Szabolcs Péter, Wim Saris, John Mathers, Edith Feskens et al., “Nutrient Status Assessment in Individuals and Populations for Healthy Aging-Statement from an Expert Workshop.” Nutrients 7, no. 12 (2015): 10491-500.

5. Eyowas Fantu, Schneider Marguerite, Yirdaw Biksegn, and Getahun Fentie. “Multimorbidity of Chronic NonCommunicable Diseases and its Models of Care in Low- and Middle-Income Countries: A Scoping Review Protocol.” BMJ 9, no. 10 (2019): e033320.

6. Appel Lawrence. “Dietary Patterns and Longevity: Expanding The Blue Zones.” Circulation 118, no. 5 (2008): 214-5.

7. Ames Bruce. “Optimal Micronutrients Delay Mitochondrial Decay and Age-Associated Diseases.” Mechanisms of Ageing and Development 131, no. 7-8 (2010): 473-9.

8. Guan Lihuan, Eisenmenger Anna, Crasta Karen et al., “Therapeutic Effect of Dietary Ingredients on Cellular Senescence in Animals and Humans: A Systematic Review.” Ageing Res Rev 95 (2024): 102238.

9. von Kobbe Cayetano. “Targeting Senescent Cells: Approaches, Opportunities, Challenges.” Aging (Albany NY)  11, no. 24 (2019): 12844-12861

10. Zhu Yi, Tchkonia Tamara, Pirtskhalava Tamar, Gower Adam et al., “The Achilles’ Heel of Senescent Cells: from Transcriptome to Senolytic Drugs.” Aging Cell 14, no. 4 (2015): 644-658.

11. Chaib Selim, Tchkonia Tamar, and Kirkland James. “Cellular Senescence and Senolytics: The Path to the Clinic.” Nature Medicine 28 (2022): 1556-1568.

12. Ji Shuaifei, Xiong Mingchen, Chen Huating, Liu Yiqiong, Zhou Laixian et al., “Cellular Rejuvenation: Molecular Mechanisms and Potential Therapeutic Interventions for Diseases.” Nature 8, no. 1 (2023): 116.

13. Mikkelsen Kathleen and Apostolopoulos Vasso. “B Vitamins and Ageing.” Subcell Biochem 90 (2018): 451-470.

14. Simonenko Sergey, Bogdanova Daria, and Kuldyushev Nikita. “Emerging Roles of Vitamin B12 in Aging and Inflammation.” Int J Mol Sci 25, no. 9 (2024): 5044.

15. Julia Kaźmierczak-Barańska. “Nutrition Can Help DNA Repair in the Case of Aging.” Nutrients 12, no. 11 (2020): 3364.

16. Picard Martin, Wallace Douglas, and Burelle Yan. “The Rise of Mitochondria in Medicine.” Mitochondrion, 30 (2016): 105–116.

17. Wesselink Vera, Koekkoek W, Grefte Sander, Witkamp Renger et al., “Feeding Mitochondria: Potential Role of Nutritional Components to Improve Critical Illness Convalescence.” Clinical Nutrition 38, no. 2 (2019): 982-995.

18. Gombart Adrian, Pierre Adaline, and Maggini Silvia. “A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection.” Nutrients 12, no. 1 (2020): 236.

19. Antonio Estrada Jose, and Contreras Irazu. “Nutritional Modulation of Immune and Central Nervous System Homeostasis: The Role of Diet in Development of Neuroinflammation and Neurological Disease.” Nutrients 11, no. 5 (2019): 1076.

20. Roth-Walter Franziska, Canani Roberto, O’Mahony Liam, Peroni Diego et al., “Nutrition in Chronic Inflammatory Conditions: Bypassing the Mucosal Block for Micronutrients.” Allergy 79, no. 2 (2023): 353-383.

21. Stumpf Franziska, Keller Bettina, Gressies Carla, and Schuetz Phillip. “Inflammation and Nutrition: Friend or Foe?” Nutrients 15, no. 5 (2023): 1159.

22. Martel Jan, Ojcius David, Ko Yun-Fei, Ke Po-Yuan et al., “Hormetic Effects of Phytochemicals on Health and Longevity.” Trends in Endocrinology and Metabolism 30,  no. 6 (2019): 335-346.

23. Chung Jay, Manganiello Vincent, and Dyck Jason. “Resveratrol as a calorie restriction mimetic: therapeutic implications.” Trends Cell Biol 22, no. 10 (2012): 546-554.

24. Miyazawa Taiki, Abe Chizumi, Burdeos Gregor, Matsumoto Akira et al., “Food Antioxidants and Aging: Theory, Current Evidence and Perspectives.” Nutraceuticals 2, no. 3 (2022): 181-204.

25. Song Lili and Zhang Shicui. “Anti-Aging Activity and Modes of Action of Compounds from Natural Food Sources.” Biomolecules 13, no. 11 (2023): 1600.

26. Donati Zeppa Sabrina, Agostini Deborah, Ferrini Fabio, Gervasi Marco, et al., “Interventions on Gut Microbiota for Healthy Aging.” Cells 12, no. 1 (2022): 34.

27. Wu Lei, Xie Xinqiang, Li Ying, Liang Tingting et al., “Gut Microbiota as an Antioxidant System in Centenarians Associated with High Antioxidant Activities of Gut-Resident Lactobacillus.” NPJ Biofilms and Microbiomes 8, no. 1  (2022): 102.

28. Calder Phillip, Carr Anitra, Gombart Adrian, and Eggersdorfer Manfred. “Optimal Nutritional Status for a Well-Functioning Immune System is an Important Factor to Protect Against Viral Infections.” Nutrients 12, no. 4 (2020): 1181.

29. Collins Nicholas, and Belkaid Yasmine. “Control of Immunity Via Nutritional Interventions.” Immunity 55, no. 2 (2022): 210-23.

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