10年前、dsm-firmenichはビタミンB3の一種であるナイアシンアミドPCを化粧品用に開発しました。 それ以来、この製品はその顕著な有効性から非常に人気があります。改良されたナイアシンアミドPCの開発により、お客様は、皮膚の不快な熱感などの潜在的な望ましくない効果を最小限に抑えながら、局所用ビタミンB3の恩恵を受けることができます。 これらは残留ニコチン酸によって引き起こされます。dsm-firmenichのブランドビタミンB3は、残留ニコチン酸が100ppm未満であることが保証されており、非常に優れた忍容性を持っています。 そして-ビタミンB3はまだ驚かせる力を持っています！dsm-firmenichの最近の独自の研究により、ビタミンB3は、環境汚染とどこにでもあるブルーライトという美容業界が直面する最新の課題に対して、強力な味方になることが明らかになりました。
公害ケア
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ブルーライトは、活性酸素種（ROS）を誘導することにより、皮膚の酸化ストレスを著しく増加させることが示された。 ROSは、タンパク質や脂質の損傷を引き起こす可能性がある。 タンパク質の場合、これはカルボニル化タンパク質の形で起こる可能性がある。 ナイアシンアミドPCは、ブルーライト照射に応答して、ヒト皮膚におけるROSおよびカルボニル化タンパク質レベルを有意に減少させることが示された。 ナイアシンアミドは、ヒトケラチノサイトおよびヒト皮膚におけるDNA損傷の修復を促進することが示された。 また、3D皮膚モデルにおいて、紫外線による免疫抑制および皮膚色素沈着の減少を防ぐ可能性がある。
During menopause, the hormonal decline takes its toll drastically on the skin.
Skin becomes thinner, collagen is significantly degraded; deep wrinkles and age spots form and skin loses water and becomes dry. All these changes often lead to a sense of discomfort and diminished self-confidence as women contend with the visible alterations in their skin's texture and appearance.
A new in vivo study from dsm-firmenich shows that Niacinamide PC is an effective solution for menopausal skin concerns. It addresses issues such as dryness, sensitivity, fine lines, wrinkles by strengthening the skin barrier and protecting against collagen degradation. Its DNA repair properties and ability to fade hyperpigmentation make Niacinamide PC ideal for menopausal women skincare routines, enhancing overall skin health and resilience during this multi-change period.
Collagen synthesis is generally reduced during menopause. Treatment with Niacinamide PC resulted in lower levels of free proline and acetyl-proline, confirming its effectiveness in preserving collagen integrity and maintaining skin elasticity.
Significant increase of free proline by 80% and significant reduction of free proline by 23% after treatment by 5% Niacinamide PC vs placebo
Browse our range of Niacinamide PC formulations.
Our facial cream is your perfect partner for your skincare routine during menopause! With Niacinamide PC and vitamins B5, B6, and B12, it restores ceramide balance, strengthens the skin's barrier, and delivers deep hydration.
With a powerful combination of Niacinamide PC and vitamins B5, C, and E, our facial serum is perfect for maintaining radiant, even-toned skin at every stage of life.
Looking for an easier way to protect your skin from daily sun damage? Check out our powerful stick!
A few drops, many benefits! This advanced formula hair serum combines the power of Niacinamide PC (0.5%) with other ingredients to provide complete and sophisticated care for menopausal women's hair and scalp.
Our facial cream is your perfect partner for your skincare routine during menopause! With Niacinamide PC and vitamins B5, B6, and B12, it restores ceramide balance, strengthens the skin's barrier, and delivers deep hydration.
With a powerful combination of Niacinamide PC and vitamins B5, C, and E, our facial serum is perfect for maintaining radiant, even-toned skin at every stage of life.
Looking for an easier way to protect your skin from daily sun damage? Check out our powerful stick!
A few drops, many benefits! This advanced formula hair serum combines the power of Niacinamide PC (0.5%) with other ingredients to provide complete and sophisticated care for menopausal women's hair and scalp.
Our facial cream is your perfect partner for your skincare routine during menopause! With Niacinamide PC and vitamins B5, B6, and B12, it restores ceramide balance, strengthens the skin's barrier, and delivers deep hydration.
With a powerful combination of Niacinamide PC and vitamins B5, C, and E, our facial serum is perfect for maintaining radiant, even-toned skin at every stage of life.
Looking for an easier way to protect your skin from daily sun damage? Check out our powerful stick!
A few drops, many benefits! This advanced formula hair serum combines the power of Niacinamide PC (0.5%) with other ingredients to provide complete and sophisticated care for menopausal women's hair and scalp.
Niacinamide PC is readily biodegradable and sustainably produced, using a unique process and bio-based raw material. This enables over 60% naturality and lowers the ingredient's carbon footprint.
PARSOL® Max (INCI: Methylene Bis-Benzotriazolyl Tetramethylbutylphenol) is a photostable broad spectrum UV filter which delivers outstanding performance that breaks through the boundaries of UVB and UVA to continue into the blue light spectrum.
Our unique peptide cosmetic ingredient SYN-UP® has excellent capacity to fight against dry skin conditions and, skin redness, due to its interaction on two common skin bacteria.
ALPAFLOR® EDELWEISS CB is an organic bioactive that protects skin barrier, enhances skin resistance to external stress factors and provides an ultimate skin sensation. It is COSMOS and NATRUE organic certified and Fair for Life fair trade certified.
Building on our strong expertise in application, dsm-firmenich formulators create desirable formulations that can be used in a variety of market applications.
Download a Safety Data Sheet (SDS) for this product.